As Diablo IV gold you level up and reach higher world tiers, Nightmare Dungeons and Horadric Vaults become your primary farming zones. These areas not only spawn tougher enemies with better drop rates, but they’re also packed with chests that can contain rare loot and vials. Horadric Vaults, in particular, are known for their high vial yield, especially when cleared on higher difficulties.

Helpout Missions
Early in the season, “Helpout” missions provide a beginner-friendly route to collect Horadric Vials. These tasks can be completed at almost any level, making them a cheap Diablo 4 Items good choice for players still building up their character.

Chests and Seasonal Rewards
Horadric Vials are also found in random world chests, seasonal stashes, and through progression in seasonal activities. The more you explore, open containers, and engage with seasonal content, the more vials you’ll accumulate over time.